Pinyin: Da Huang  Chinese: 大黄
Pharmaceutical: Radix et Rhizoma Rhei
Taxonomy: Rheum palmatum
English: Chinese Rhubarb Root

Tastes: Bitter, cold
Meridians Entered: Large Intestine, Spleen, Stomach, Liver and Heart

Actions & Indications:

1. Drains Heat and purges accumulations
   Intestinal Heat Excess, with high fever, profuse sweating, thirst, constipation, abdominal distention and pain, delirium, a yellow tongue coat and a full pulse
   Yang-Ming Fu Stage
   Qi Level Heat in the Intestines
2. Drains Fire
   Fire from Excess with intense fever, sore throat, and painful eyes and constipation
   Fire toxin sores due to Xue Level Heat, especially with constipation
3. Clears Heat, transforms Dampness and promotes urination
   Damp-Heat with oedema, jaundice, painful urinary dysfunction and acute, hot dysenteric disorders
4. Drains Heat from the Blood
   Bloody stool either from hemorrhoids or Heat in the Intestines
   Chaotic movement of hot Blood with hemoptysis or epistaxis with constipation
   It can be powdered and administered orally for bleeding in the upper digestive tract
5. Invigorates the Blood and dispels Blood Stasis
   Blood Stasis with amenorrhea, fixed abdominal masses or fixed pain
   Blood Stasis due to traumatic injury
   Intestinal abscess
6. Clears Heat and reduces Fire toxicity
   Topically or internally for burns or skin lesions (Chuang Yung) due to Heat
7. Clears Heat and eliminates Phlegm
   Chronic Accumulation of Phlegm-Heat with cough, dyspnea, mania, disorientation and other symptoms of Phlegm Misting the Heart

Standard Dosage: 10-15g in decoction. Excessive decoction will reduce the purgative action. Therefore it should be added at end to achieve this purpose and over-decocted to eliminate this action.
Cautions: It should be used with caution in case of spleen and stomach deficiency for its bitter and cold property which is easily to damage stomach qi. It is contraindicated to women during pregnancy, menstruation or lactation for it has actions of activating blood and resolving stasis, and can make the purged substances follow lactating out.

Pinyin: Dang Gui  Chinese: 當歸
Pharmaceutical: Radix Angelicae sinensis
Taxonomy: Angelica sinensis
English: Chinese Angelica Root / Tang-Kuei / Dong Quai Root

Tastes: Sweet, Pungent, Warm
Meridians Entered: Heart and Liver

Actions & Indications:

1. Tonifies the Blood and regulates the menses
   Blood Deficiency, especially when affecting the Heart and Liver with pale, ashen complexion, lusterless nails, tinnitus, blurred vision and palpitations
   Blood Deficiency associated irregular menstruation, amenorrhea and dysmenorrhea
2. Invigorates and harmonizes the Blood and disperses Cold (stops pain due to Blood Stasis)
   Blood Stasis causing abdominal pain and carbuncles and pain due to Blood Stasis from traumatic injury, especially when accompanied by Deficiency Cold
   Postpartum menstruation
   Pregnancy (use with caution)
   Blood Deficiency with chronic Wind-Damp-Bi
3. Moistens the Intestines and unblocks the bowels
   Dry Intestines due to Blood Deficiency
4. Reduces swelling, expels pus, generates flesh and alleviates pain
   Sores and abscess (Chuang Yung), internally and topically
5. Stops coughing and treats dyspnea
   Used adjunctively for coughing
6. Tonifies the Blood while suppressing Parasites
   Gu Sydnrome (Fruehauf, 1998)
   Chronic inflammatory disease (Fruehauf, 2015)

Standard Dosage: 6-12g in decoction.
Cautions: It is contraindicated in cases of Damp-Heat stagnating in the Middle, Lung Heat with Phlegm Fire, and Yin deficiency with effulgent Yang because it is warm and sweet in properties. In addition, it should be used with caution in cases of loose stool because it can moisten intestines to smooth stool.

Many sources recommend using caution, avoiding or only taking under guidance of a TCM physician during pregnancy as it can cause uterine contractions. However, there are no studies supporting this and the only scientific literature seems to suggest that Z-Ligustilide has anti-spasmodic activities that alleviate dysmenorrhoea by inhibiting uterine contractions (Du et al., 2006; Dietz et al., 2016).

Caution is also advised in breast cancer patients due to its oestrogen stimulating activity. This based upon Lau et al (2005) who found it may stimulate breast cancer growth in vitro, however Yue et al, (2019) demonstrated that it is not that stimulatory in breast cancer both in vitro and in vivo through a series of tests, although they suggested it should still be used with caution in estrogen receptor-positive breast cancer. Conversely, a large population study in Taiwan by Wu et al (2014) found it reduced the subsequent risk of endometrial cancer in breast cancer survivors taking tamoxifen, especially in those of reproductive age.

Pinyin: Gan Cao  Chinese: 甘草
Pharmaceutical: Radix Glycyrrhizae
Taxonomy: Glycyrrhiza uralensis seu glabra seu inflata
English: Liquorice Root

Tastes: Sweet, slightly cold
Meridians Entered: Heart, Lung and Spleen (and all 12 meridians)

Actions & Indications:

1. Tonifies the Spleen and augments Qi
   Spleen Qi Deficiency with shortness of breath, lassitude and loose stools
   Qi and Blood Deficiency with an irregular pulse and/or palpitations
   Heart Qi Deficiency or Heart Yang Deficiency
2. Moistens the Lungs, resolves Phlegm and stops coughing
   Lung Heat or Cold
   Productive or non-productive coughing
3. Moderates spasms and alleviates pain
   Painful muscle spasms of the abdomen and legs
4. Clears Heat and relieves Fire Toxicity
   Raw for Toxic Heat with sore throat or carbuncles and sores (Chuang Yung)
5. Antidote for many toxic substances (internal and topical)
   Poisoning
   Bites (after washing the wound, chew Gan Cao and apply a thick layer on the bite wound, changing whenever it dries out; Bao Xiang-Ao, 1846, New Compilation of Proven Formulas)
6. Moderates and harmonizes the harsh properties of other herbs and guides the herbs to all twelve channels
   Often added in small doses to harmonise formulas
7. Tonifies the Qi while suppressing Parasites
   Gu Sydnrome (Fruehauf, 1998)
   Chronic inflammatory disease (Fruehauf, 2015)
8. Aids fasting
   Mentioned in the Shen Nong Ben Cao Jing as part of the superior class of herbs which can, with protracted taking, make the body light and prolong life. This may suggest it was part of supplementing the diet when engaging in an "avoiding grain" (Bigu 辟穀) fasting regime to cultivate life (Yangsheng 養生).

Standard Dosage: Typically 1.5-9g in decoction. Large doses can be up 30g.
Cautions: It is contraindicated for combining with Hai Zao, Da Ji, Gan Sui and Yuan Hua because of "eighteen antagonisms". It is also contraindicated in cases of dampness obstruction in middle energizer and edema because it can help dampness obstruct qi, and it is prohibited from long-term usage in large dosage (more than 20g/day) and should be avoided or used with extreme caution in patients with high blood pressure because it may raise aldosterone levels in the blood causing retention of sodium.

The NHS recommends avoiding during pregnancy.

Pinyin: Chi Shao  Chinese: 赤芍
Pharmaceutical: Radix Paeoniae Rubra
Taxonomy: Paeonia lactiflora seu veitchii
English: Red Peony Root

Tastes: Bitter, pungent, light cold
Meridians Entered: Liver

Actions & Indications:

1. Clears Heat and cools the Blood
   Xue Stage Heat Stage Heat or Blood Heat with fever, a purple tongue, maculae, hemorrhage and Blood Heat gynecological problems
2. Clears Liver Fire and relieves eye pain
   Liver Fire with redness, swelling and pain of the eyes
3. Reduces swelling from sores and abscesses
   Early stage abscesses and boils
4. Eliminates Evil Qi, breaks up Blood Stasis, disperses accumulations and fortifies Qi
   The Shen Nong Ben Cao Jing places this in the middle class of herbs and says that "It mainly treats Evil Qi and abdominal pain, eliminates blood impediment, breaks hard gatherings and cold and heat mounting conglomeration, relieves pain, disinhibits urination, and boosts the qi.

Standard Dosage: 6-12g in decoction.
Cautions: It is antagonistic to Li Lu. It should be used with caution in hot skin conditions where it may aggravate by "fanning the flames". Caution with anticoagulants as it may slow clotting time. May also slow the absorption of phenytoin.