The Eighteen Pathologies are diseases that can affect any system, mentioned by Zhang Zhongjing in the introduction to the Jin Gui Yao Lue, lines 16-18.
The student asks "Yang diseases are 18, what does this mean (陽病十八,何謂也)?" to which the Master replies that these are:
| 頭痛 Tou Tong: | Headache, | |
| 項 Xiang: | Neck, | |
| 腰 Yao: | Waist, | |
| 脊 Ji: | Spine, | |
| 臂 Bi: | Arm and | |
| 腳 Jiao: | Foot | |
| 掣痛 Che Tong: | Pulling pain |
Next, the Student asks: "Yin diseases are 18, what does this mean (陰病十八,何謂也)?" to which the Master replies:
| 欬 Kai: | Cough | |
| 上氣 Shang Qi: | Rising Qi | |
| 喘 Chuan: | Wheezing | |
| 噦 Hui: | Vomiting | |
| 咽 Yan: | Sore throat | |
| 腸鳴 Chang Ming: | Bowel sounds | |
| 脹滿 Zhang Man: | Distention | |
| 心痛 Xin Tong: | Heart pain | |
| 拘急 Ju Ji: | Sudden arrest |
It is notable that these do not add up to 18. All that is certain is that the Yang diseases are Exterior, muskuloskeletal disorders while the Yin diseases refer to Internal dysfunctions of the Zangfu (臟腑). While only the Zang are mentioned specifically, the symptoms given appear to include various Fu, especially "vomiting" that comes from the Stomach and "bowel sounds" from the Intestines, and seem to be included as subordinates of the Zang.
The Yang diseases could be extrapolated to 18 if "arm" and "foot" counts all 6 joints on the limbs (shoulders, elbows & wrists on the upper; hips, knees, ankles on the lower) on both sides to make 12 plus fingers and toes counted as two grouped entities to make 14, plus head, neck, waist and spine (+4 = 18). These are probably what is referred to as the Six Minors (六微) since their diseases are less severe and the Channel system is divided into Six Divisions (六經) which all cross those areas making 108 possible disease patterns for muskuloskeletal pain patterns and headaches.The Yin Diseases only list 9 and many of these are referring to one specific system. However, if the pathomechanism behind each symptom is identified, then they may be referring to a set of universal pathomechanisms that can affect any Zang or Fu, using the most exemplary manifestation as an example. This would then make 18 disorders for each pair (9 each).
What remains is to decipher the pathomechanism implied by each symptom given. My interpretation is as follows:
| 欬 Kai: | Cough | 滯 Shi: | Excess / Stagnation | |||
| 上氣 Shang Qi: | Rising Qi | 逆: Ni: | Rebellion / Counterflow | |||
| 喘 Chuan: | Wheezing | 虛 Xu: | Deficiency / Emptiness | |||
| 噦 Hui: | Vomiting | 滑脱 Hua Tuo: | Leakage / Loss | |||
| 咽 Yan: | Sore throat | 熱 Re: | Heat | |||
| 腸鳴 Chang Ming: | Bowel sounds | 風 Feng: | Wind | |||
| 脹滿 Zhang Man: | Distention | 濕 Shi: | Dampness | |||
| 心痛 Xin Tong: | Heart pain | 失神 Shi Shen: | Loss of Shen aspect | |||
| 拘急 Ju Ji: | Sudden arrest | 厥 Jue: | Reversal / Sense Obstruction |